Abstract: In view of the geological features of reservoirs with low porosity and low permeability in Baobei block in Baolang oilfield and production complexities such as the large number of oil layers, long oil layer distribution interval and scattered oil layers, we studied the technical and economical limits of layer series division and combination in Baobei block including effective thickness, number of oil layers, single well productivity and single well controlled geologic reserves. Optimization of layer series division and combination was performed and optimal development layer series were selected.