Abstract: Based on comprehensive logging data, well logging data and core data, this paper studies the heterogeneity of Chang 6_3 oil reservoir in Wuqi oilfield of Ordos basin from three aspects of intramedullary heterogeneity, interlayer heterogeneity and plane heterogeneity. The results show that the intramedullary heterogeneity in the Chang 6_3 reservoir in Wuqi oilfield is strong, mainly due to the development of interlayer, which is parallel bedding and inclined bedding. The permeability heterogeneity in the layer is strong, and the interlayer in the layer is developed. The interlayer heterogeneity of Chang 6_3 reservoir is different, and the heterogeneity of Chang 6_3~2 is better than that of Chang 6_3~1. The plane heterogeneity of Chang 6_3 reservoir is strong, which is reflected in the distribution of sand body and physical properties, mainly because of the sedimentary microfacies types.