Abstract: Biolimestone in Changdi block of eastern Zhanhua sag is relatively thin, and the previous research methods cannot effectively identify and predict the distribution range of Biolimestone. Based on the method of seismic facies research, by using drilling, logging and seismic data, the seismic facies characteristics and prediction technology of Biolimestone in the first member of Shahejie formation of Changdi uplift in eastern Zhanhua sag are systematically studied. Biolimestone in Changdi block can be divided into seismic phases: wedge-shaped phase, filling phase, continuous sheet phase with medium sheet phase with strong amplitude and continuity. Each type of seismic facies corresponds to different seismic reflection characteristics. The sensitive parameters of Biolimestone are extracted by using different properties and the possible thickness of Biolimestone in the whole study area is calculated to determine the planar thickness distribution characteristics of Biolimestone. The geological model is tested by wave equation forward simulation, and the result is in good agreement with the actual data.