Abstract: The block Su 53 in Sulige gas field is a typical low-pressure,low-permeability,low-abundance,strong heterogeneity gas reservoir. The rational well space of gas field has been determined though the method of economic limitsand reasonable of gas production rate which is used in calculation of technological rational well pattern and space,combined with numerical simulation studies and field test results. The paper proposed development program: Reservesabundance higher than 1.3 ×10 8 m 3/km2 area using 600m ×800 m well pattern similar to a diamond-shaped irregular shape,focus on building production,reserves abun-dance of less than 1.3 ×108 m 3/km2 region using the first600 m ×1 200 m similar to diamond irregular network con-trol wells.