Abstract: Due to long-term adoption of one series of strata development in Zhonger block of Chengdao oilfield,problems such as imperfect well pattern,interlayer interference,low oil production speed and etc became prominent.In order to enhance oil production speed and oil recovery rate,a comprehensive adjustment such as strata series subdivision and well pattern infilling has been adopted since 2009.Besides the comprehensive adjustment,other technique means such as optimized perforation interval,popularization and application of horizontal wells,timely implementation of old well,timely liquid extract in oil wells have been applied and then the development effect has been obviously achieved.Comprehensive analysis believes that the practices of the adopted adjustment technology can meet the needs of high efficient development in the area at present.