Abstract: Liquid enhanced is very important to explore the potential in middle and high water-cut stage of heavy oil reservoir. The optimal selection of fluid enhanced well location is the premise to do a good job in fluid enhanced of heavy oil reservoir. At present, the selected fluid enhanced wells are mainly determined by the index curve of dimensionless oil production and fluid production. The evaluation is relatively simple,without considering the mutual restriction between the various factors. According to the comprehensive analysis of the factors that affect the liquid enhanced effectiveness, the influencing factors mainly include average permeability, net pay thickness, permeability contrast, distance from edge water, water-cut, oil production, formation-saturation pressure difference, production drawdown pressure and remaining wellcontrolled reserves. Then the fuzzy evaluation method is used to optimize the liquid enhanced wells. The result shows that the dynamic factors have a significant impact on the liquid enhanced effectiveness, while the static factors have less influence. The research has been applied in J oilfield and the enhanced oil production effect of single well was good.