Abstract: Tiaohu formation of Ma-56 block in Santanghu of Tuha oilfield is mainly of dense limestone reservoir.Based on fracture orientation and fracture reservoir prediction,by use of slippery water + weak crosslinking system,the staged fracturing technology of natural fractures with large displacement,low sand ratio and communication has been implemented.Through the adoption of lead acid pretreatment technology,drag-reducing fluid technology with multiple slugs,fast break gelling technology,small particle size combination ceramsite and downhole micro-seismic test technology,a breakthrough has been achieved in fracturing of multiple sections with horizontal wells in Ma-56 block,and it laid the foundation for the efficient oilfield development.