Abstract: The survey lines of regional seismic profile in Nanxiang basin cross different tectonic units,which is different in bur- ial depth and large variation in range,therefore the geolog- ical settings in different units should be suitable to different acquisition methods.On the basis of adequate analytic dem- onstration and field test,a layout of gradual modification, which is designed segment by segment in accordance with tectonic variation and burial depth of target strata,is ad- vanced and brings an appreciable effect in the field seismic acquisition.