Abstract: Xinchang shaximiao gas reservoir is one of the main gas reservoir in southwest field,which has entered intermediary and later stage of production decline at present.Parameters optimization of infill well fracturing has been proposed for post fracturing response to guarantee fracturing effects,includeing target fracture length,gravel inputting scale,pre-liquid ratio,average sand ratio,and delivery capacity after development adjustment applications.Optimiza-tion technology is successfully applied to seven wells such as well CX606,which success rate is 100%.Good effect of increase production has been acquired by the technology with-out well interference providing an effective technology for infill well fracturing in xinchang shaximiao gas reservoir.